Labware Detergents and Cleaners
Medchemexpress LLC LYG-409 | 3053857-55-6 | 98.1% | 515.44 | 100 MG
LYG-409 is an orally active degrader of GSPT1. It has demonstrated excellent anti-acute myeloid leukemia and prostate cancer activity in vivo, with Tumor Growth Inhibition (TGI) rates of 94.34% and 104.49%, respectively. In vitro, it inhibits KG-1 cells through the degradation of GSPT1, exhibiting an IC50 of 9.50 nM and a DC50 of 7.87 nM.
- Orally active GSPT1 degrader.
- Shows excellent anti-acute myeloid leukemia and prostate cancer effects in vivo.
- Inhibits KG-1 cells through GSPT1 degradation.
- For research use only.
![Medchemexpress LLC Butanoic acid, 4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]... | 2135640-92-3 | 98.0% | C28H26ClF3N2O6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259893.png-250.jpg)
Medchemexpress LLC Butanoic acid, 4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]... | 2135640-92-3 | 98.0% | C28H26ClF3N2O6 | 10MG
(-)-JNJ-A07 is an enantiomeric small-molecule inhibitor of dengue virus (DENV) replication, reported to have an EC50 of 31 nM. Supplied as a purified solid (CAS 2135640-92-3) with molecular formula C28H26ClF3N2O6, it is suitable for in vitro and in vivo research and can be formulated in DMSO or combination vehicles for dosing.
Casey Company SPEEDBALL 2000 1/QT BOTTLE
Speedball 2000 Power Cleaner 32 oz. Ready-to-use, non-butyl, heavy-duty power cleaner. Yellow in color with a citrus scent. Low-odor formula.
Electron Microscopy Sciences Micro Cleaning Solution 1 GL
Specially designed for ultrasonic cleaning machines. Cleans glass, most metals, plastics, and rubber. You can work with any concentration. Contains no phosphates and it is biodegradable. Even removes radioactive contaminants. Not to be used on zinc, magnesium, or aluminum.
Medchemexpress LLC LYG-409 | 3053857-55-6 | 98.1% | 515.44 | 5 MG
LYG-409 is an orally active degrader of GSPT1. It demonstrates excellent anti-acute myeloid leukemia and prostate cancer activity in vivo, with TGI percentages of 94.34% and 104.49%, respectively. In vitro, it inhibits KG-1 cells through the degradation of GSPT1, showing an IC50 of 9.50 nM and a DC50 of 7.87 nM.
- Orally active degrader of GSPT1.
- Exhibits anti-acute myeloid leukemia and prostate cancer activity in vivo.
- Inhibits KG-1 cells by degrading GSPT1.
Medchemexpress LLC Lyg-409 | 3053857-55-6 | 98.1% | 515.44 | 1 ML
LYG-409 is an orally active degrader of GSPT1. It demonstrates excellent anti-acute myeloid leukemia and prostate cancer activity in vivo, with TGI of 94.34% and 104.49%, respectively. It inhibits KG-1 cells by degrading GSPT1, with an IC50 of 9.50 nM and a DC50 of 7.87 nM in vitro.
- Orally active degrader of GSPT1
- Excellent anti-acute myeloid leukemia and prostate cancer activity in vivo
- Inhibits KG-1 cells mediated by GSPT1 degradation
Medchemexpress LLC (+)-JNJ-A07 | 2135640-93-4 | 98.46% | 578.96 | 25 MG
(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor that targets the NS3-NS4B interaction. It demonstrates nanomolar to picomolar activity against 21 clinical isolates and exhibits a favorable pharmacokinetic profile, leading to significant efficacy against dengue virus infection in mouse models.
- Targets NS3-NS4B interaction
- Potent pan-serotype dengue virus inhibitor
- Effective against 21 clinical isolates
- Favorable pharmacokinetic profile
- High barrier to resistance
- Inhibits viral replication complex formation